Search results for "metabolic therapy"

showing 3 items of 3 documents

Pharmacological Therapy of Non-Alcoholic Fatty Liver Disease: What Drugs Are Available Now and Future Perspectives

2019

The non-alcoholic fatty liver disease (NAFLD) is rapidly becoming the most common cause of chronic liver disease as well as the first cause of liver transplantation. NAFLD is commonly associated with metabolic syndrome (MetS), and this is the most important reason why it is extremely difficult to treat this disease bearing in mind the enormous amount of interrelationships between the liver and other systems in maintaining the metabolic health. The treatment of NAFLD is a key point to prevent NASH progression to advanced fibrosis, to prevent cirrhosis and to prevent the development of its hepatic complications (such as liver decompensation and HCC) and even extrahepatic one. A part of the we…

CirrhosisHealth Toxicology and Mutagenesismedicine.medical_treatmentlcsh:MedicinePhysical exerciseDiseaseReviewLiver transplantationChronic liver diseaseHepatic ComplicationBioinformaticsmetabolic syndrome03 medical and health sciences0302 clinical medicineNon-alcoholic Fatty Liver DiseasemedicineAnimalsHumans030304 developmental biology0303 health sciencesbusiness.industryFatty liverlcsh:RPublic Health Environmental and Occupational Healthnutritional and metabolic diseasesmedicine.diseasedigestive system diseasesmetabolic therapy030211 gastroenterology & hepatologyMetabolic syndromebusinessInternational Journal of Environmental Research and Public Health
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Pleural epithelioid angiosarcoma with lymphatic differentiation arisen after radiometabolic therapy for thyroid carcinoma: immunohistochemical findin…

2017

Abstract Background Pleural angiosarcoma is a rare tumor that causes diffuse pleural thickening and effusion, mimicking mesothelioma. Immunohistochemistry is needed to highlight endothelial differentiation. We describe the first case of pleural angiosarcoma with lymphatic differentiation following radiometabolic therapy for thyroid carcinoma. Case presentation A 50-year-old man showed diffuse pleural thickening and effusion. Nine years earlier, he underwent thyroidectomy and radiometabolic therapy for thyroid carcinoma with lymph node metastases. Histologically, the tumor consisted of a solid proliferation of atypical epithelioid cells and anastomosed vascular spaces, lacking of red blood c…

Male0301 basic medicinePathologymedicine.medical_specialtyNeoplasms Radiation-InducedHistologyPleural NeoplasmsHemangiosarcomaReviewRadiometabolic therapyPathology and Forensic MedicineIodine RadioisotopeIodine RadioisotopesThyroid carcinoma03 medical and health sciences0302 clinical medicinelcsh:PathologymedicineHumansAngiosarcomaThyroid NeoplasmsMesotheliomaPleural NeoplasmPleural angiosarcomaPleural NeoplasmLymph nodebusiness.industryThyroid CarcinomaGeneral MedicineMiddle Agedmedicine.diseaseImmunohistochemistryCarcinoma Papillary030104 developmental biologymedicine.anatomical_structureHemangiosarcomaLymphatic systemThyroid Cancer Papillary030220 oncology & carcinogenesisbusinessEpithelioid celllcsh:RB1-214HumanDiagnostic Pathology
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Continuous subcutaneous Insulin infusion leads to immediate, table, and long-term changes in metabolic control

2008

Background:  Evaluations of continuous subcutaneous insulin infusion (CSII) usually focus on one pre- and one post-CSII measurement to assess metabolic therapy outcome. Aim:  Extending this research, the aim of the present study was to provide a more fine-grained analysis of achieved glycaemic control. Methods:  In 52 patients with type 1 diabetes (mean age of 37.85 years at CSII begin; s.d. ± 12.41), haemoglobin A1c (HbA1c) levels were assessed every 3 months over a period of 5 years (1 year before and 4 years after the introduction of CSII). Mixed models were utilized to describe changes in glycaemic control. Results:  The pre–post course showed that already in the first quarter, a statis…

mixed modelsAdultBlood GlucoseMalemedicine.medical_specialtyPediatricstype 1 diabetesEndocrinology Diabetes and MetabolismModels BiologicalDrug Administration ScheduleTimeHba1c levelEndocrinologyDiabetes mellitusInternal Medicinemedicinefollow upHumansHypoglycemic AgentsInsulinAge of OnsetGlycated HemoglobinType 1 diabetesHaemoglobin A1cbusiness.industry10093 Institute of PsychologyCSIIMean ageInfusion Pumps ImplantableMiddle AgedPrognosismedicine.diseaseSubcutaneous insulinSurgery1310 Endocrinologylong-term changes2712 Endocrinology Diabetes and MetabolismDiabetes Mellitus Type 1Treatment Outcome2724 Internal MedicineMetabolic control analysisFemalebusiness150 PsychologyFollow-Up StudiesMetabolic therapy
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